WP Asset Clean Up decreases the number of HTTP requests per page and makes your code cleaner. It might even help reduce conflicts between your plugins. Once you install the plugin, it analyzes your files and lets you choose which ones not to load. You can change what loads up on each page once you edit it.
As you can see in the above screenshot, the WP Asset Clean Up plugin marks WordPress core files to make your life easier. The plugin is compatible with WordPress multisite networks. This is a free plugin.